Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536948 | 0.83 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2ESR1ESR2GRIN2D | |
| SCHEMBL6537130 | 0.66 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL29531709 | 0.59 | CRHBP (0.41) | ALDH1A1SMN1; SMN2ESR1ESR2KCNH2 | |
| SCHEMBL11229648 | 0.58 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2ESR1ESR2GRIN1 | |
| SCHEMBL14498998 | 0.58 | POLB (0.50) | ALDH1A1KCNH2POLBTSHRCYP2C19 | |
| SCHEMBL19718061 | 0.58 | GRIN1 (0.40) | ALDH1A1SMN1; SMN2ESR1ESR2GRIN1 | |
| SCHEMBL11494560 | 0.57 | MMP2 (0.38) | ALDH1A1SMN1; SMN2BACE1LMNAGAA | |
| SCHEMBL13045977 | 0.57 | ALDH1A1 (0.60) | ALDH1A1POLBLMNATSHRCYP2C19 | |
| SCHEMBL11930003 | 0.56 | CYP19A1 (0.44) | ALDH1A1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL22215578 | 0.56 | ELANE (0.38) | ALDH1A1POLBGPR55LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696234-B2 | Silver halide photosensitive material and isothiazolidine-3-one derivative | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20030190566-A1 | Silver halide photosensitive material and isothiazolidine-3-one derivative | FUJI PHOTO FILM CO., LTD. | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030190566-A1 | Silver halide photosensitive material and isothiazolidine-3-one derivative | NRP1, NR2E3, SCN1B | ALDH1A1 172/4885SMN1; SMN2 3343/4885ESR1 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.