SCHEMBL6537009

SCHEMBL6537009

CC(O)CCCc1ccccc1C(=O)Cl

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 1/20 0.38
FOLH1 Q04609 1/20 0.38
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.36
SLC16A3 O15427 3/20 0.35
POLB P06746 1/20 0.35
ADRB2 P07550 5/20 0.34
ADRB1 P08588 5/20 0.34
TSHR P16473 2/20 0.34
CYSLTR2 Q9NS75 1/20 0.34
CYSLTR1 Q9Y271 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8094593 0.84 SLC16A3 (0.38) ALDH1A1ALOX15FOLH1KMT2ALMNA
SCHEMBL17272972 0.83 ALDH1A1 (0.46) ALDH1A1ALOX15FOLH1LMNASLC16A3
SCHEMBL11628620 0.81 ALDH1A1 (0.38) ALDH1A1ALOX15FOLH1KMT2ALMNA
SCHEMBL28323431 0.80 ADRB2 (0.41) ALDH1A1LMNAADRB2ADRB1TSHR
SCHEMBL3181025 0.80 TSHR (0.44) ALDH1A1ALOX15FOLH1LMNATSHR
SCHEMBL9770541 0.79 SLC16A3 (0.52) ALDH1A1FOLH1SLC16A3TSHRCYSLTR2
SCHEMBL8033375 0.78 LIPG (0.51) ALDH1A1LMNATSHRCYSLTR2CYSLTR1
SCHEMBL963965 0.77 LIPG (0.54) ALDH1A1LMNATSHRCYSLTR2CYSLTR1
SCHEMBL8093495 0.77 LIPG (0.54) ALDH1A1LMNATSHRCYSLTR2CYSLTR1
SCHEMBL9560320 0.77 LIPG (0.54) ALDH1A1LMNATSHRCYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040233377-A1 Liquid crystal display device COGNOA, INC. 2004-11-25 US disclosed
US-6757044-B2 Liquid crystal display device with spacers controlling thickness of liquid crystal layer HITACHI, LTD. (JP) 2004-06-29 US disclosed
US-20030002005-A1 Liquid crystal display device with spacers controlling thickness of liquid crystal layer IPS ALPHA SUPPORT CO., LTD. (JP) 2003-01-02 US disclosed
US-6441880-B1 Normally closed liquid crystal display device using spacers coated with material having liquid crystal aligning ability by irradiation with polarized light HITACHI, LTD. (JP) 2002-08-27 US disclosed