SCHEMBL6537077

SCHEMBL6537077

C/C=C/CN1C(=O)C=CC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
BLM P54132 2/20 0.48
GMNN O75496 1/20 0.48
THPO P40225 1/20 0.48
PMP22 Q01453 1/20 0.48
FAAH O00519 5/20 0.42
HPGD P15428 2/20 0.41
HSP90AA1 P07900 1/20 0.41
TLR9 Q9NR96 1/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
XBP1 P17861 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9181540 1.00 MGLL (0.48) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL3813599 0.76 MGLL (0.44) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL9414034 0.76 MGLL (0.42) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL1955696 0.76 MGLL (0.42) MGLLALDH1A1LMNAMAPTNPSR1
Hydrochloric Acid SCHEMBL10491231 0.74 MGLL (0.41) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL8024157 0.74 MGLL (0.41) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL11560070 0.71 FAAH (0.38) MGLLFAAHRAB9ASMN1; SMN2CA12
SCHEMBL21410483 0.71 FAAH (0.38) MGLLFAAHRAB9ASMN1; SMN2CA12
SCHEMBL6140235 0.71 MGLL (0.39) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL7785636 0.71 MGLL (0.39) MGLLALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6765049-B2 POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS, CLAY IS PARTIALLY EXFOLIATED WITHIN AND SURFACTANTS; THICKENERS, DISPERSANTS, PLASTICS ADDITIVES, ADHESIVES, COATINGS, FLEXOGRAPHIC INKS, OVERPRINT VARNISHES, AND DRY CEMENT POWDER ROHM AND HAAS COMPANY 2004-07-20 US claimed
EP-1325037-A2 HIGH ACID AQUEOUS NANOCOMPOSITE DISPERSIONS ROHM AND HAAS COMPANY (US) 2003-07-09 EP claimed
US-20020055580-A1 High acid aqueous nanocomposite dispersions ROHM AND HAAS COMPANY 2002-05-09 US claimed
WO-2002024757-A2 HIGH ACID AQUEOUS NANOCOMPOSITE DISPERSIONS ROHM AND HAAS COMPANY (US) 2002-03-28 WO claimed
EP-0786494-A2 Formed article with an improved resistance against stress cracking ATOHAAS HOLDING C.V. (NL) 1997-07-30 EP claimed
US-5403894-A An alkali-soluble emulsion polymer shell and an aqueous-insoluble emulsion polymer core which are grafted by utilizing a polyfunctional compound; a cement modifier ROHM AND HAAS COMPANY (US) 1995-04-04 US claimed
EP-0348565-B1 Polymers comprising alkali-insoluble core/alkali-soluble shell and compositions thereof ROHM & HAAS (US) 1995-03-22 EP claimed
US-5266646-A Thickeners for waterbase paints; viscosity stabilizers to colorants; heat resistance; blister resistance; color float; syneresis resistance ROHM AND HAAS COMPANY (US) 1993-11-30 US claimed
US-5212251-A Sequential emulsion polymerization of unsaturated compounds having acid-ionizable functionality to make core acid insoluble and shell acid soluble; protective coatings; inks; clear overprint varnishes; paper and fiber treatment ROHM AND HAAS COMPANY (US) 1993-05-18 US claimed
EP-0279724-B1 MULTILAYERED COMPOSITE COPOLYMER WITH BIMODAL PARTICLE DISTRIBUTION, ITS PREPARATION FOR THE REINFORCEMENT OF THERMOPLASTIC MATRICES ELF ATOCHEM S.A. (FR) 1993-04-28 EP claimed
EP-0277874-B1 COMPOSITE COPOLYMER, ITS PREPARATION PROCESS AND ITS USE IN THE REINFORCEMENT OF RIGID THERMOPLASTIC MATRICES ELF ATOCHEM S.A. (FR) 1993-04-28 EP claimed
US-4897449-A POLYMERS/SHELL-CORE/ NORSOLOR (FR) 1990-01-30 US claimed
EP-0348565-A1 Polymers comprising alkali-insoluble core/alkali-soluble shell and compositions thereof ROHM AND HAAS COMPANY (US) 1990-01-03 EP claimed
US-4876313-A FOR INKS, COATINGS, VARNISHES,CEMENTS, LEATHER; ACRYLIC ACIDS, ANHYDRIDES AND OTHER UNSATURATED MONOMERS ROHM AND HAAS COMPANY 1989-10-24 US claimed
EP-0279724-A2 Multilayered composite copolymer with bimodal particle distribution, its preparation for the reinforcement of thermoplastic matrices ELF ATOCHEM S.A. (FR) 1988-08-24 EP claimed
EP-0277874-A2 Composite copolymer, its preparation process and its use in the reinforcement of rigid thermoplastic matrices ELF ATOCHEM S.A. (FR) 1988-08-10 EP claimed
US-6765049-B2 POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS, CLAY IS PARTIALLY EXFOLIATED WITHIN AND SURFACTANTS; THICKENERS, DISPERSANTS, PLASTICS ADDITIVES, ADHESIVES, COATINGS, FLEXOGRAPHIC INKS, OVERPRINT VARNISHES, AND DRY CEMENT POWDER ROHM AND HAAS COMPANY 2004-07-20 US disclosed
US-20020055580-A1 High acid aqueous nanocomposite dispersions ROHM AND HAAS COMPANY 2002-05-09 US disclosed
EP-0279724-A2 Multilayered composite copolymer with bimodal particle distribution, its preparation for the reinforcement of thermoplastic matrices ELF ATOCHEM S.A. (FR) 1988-08-24 EP disclosed
EP-0277874-A2 Composite copolymer, its preparation process and its use in the reinforcement of rigid thermoplastic matrices ELF ATOCHEM S.A. (FR) 1988-08-10 EP disclosed