SCHEMBL8024157

SCHEMBL8024157

C[SiH]([O])C=CCN1C(=O)C=CC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
BLM P54132 2/20 0.41
GMNN O75496 1/20 0.41
THPO P40225 1/20 0.41
PMP22 Q01453 1/20 0.41
FAAH O00519 5/20 0.37
HPGD P15428 2/20 0.35
HSP90AA1 P07900 1/20 0.35
TLR9 Q9NR96 1/20 0.35
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6537077 0.74 MGLL (0.48) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL3813599 0.70 MGLL (0.44) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL822301 0.70 MGLL (0.42) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL1955696 0.70 MGLL (0.42) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL4595331 0.66 MGLL (0.48) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL7785636 0.65 MGLL (0.39) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL6140235 0.65 MGLL (0.39) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL756295 0.65 AKR1B1 (0.43) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL21170285 0.65 MGLL (0.38) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL88581 0.64 CASP3 (0.48) MGLLALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6068929-A Radiation-curing or heat-curing organosiloxane compositions containing (methyl) styrene groups WACKER-CHEMIE GMBH (DE) 2000-05-30 US disclosed