SCHEMBL9181540

SCHEMBL9181540

CC=CCN1C(=O)C=CC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
BLM P54132 2/20 0.48
GMNN O75496 1/20 0.48
THPO P40225 1/20 0.48
PMP22 Q01453 1/20 0.48
FAAH O00519 5/20 0.42
HPGD P15428 2/20 0.41
HSP90AA1 P07900 1/20 0.41
TLR9 Q9NR96 1/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
XBP1 P17861 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6537077 1.00 MGLL (0.48) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL3813599 0.76 MGLL (0.44) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL9414034 0.76 MGLL (0.42) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL1955696 0.76 MGLL (0.42) MGLLALDH1A1LMNAMAPTNPSR1
Hydrochloric Acid SCHEMBL10491231 0.74 MGLL (0.41) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL8024157 0.74 MGLL (0.41) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL11560070 0.71 FAAH (0.38) MGLLFAAHRAB9ASMN1; SMN2CA12
SCHEMBL21410483 0.71 FAAH (0.38) MGLLFAAHRAB9ASMN1; SMN2CA12
SCHEMBL6140235 0.71 MGLL (0.39) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL7785636 0.71 MGLL (0.39) MGLLALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102351481-A Method for enhancing the water repellency of inorganic hydraulic binder compositions and compositions obtainable by said method and their uses RHODIA CHIMIE SA 2012-02-15 CN claimed
CN-100478409-C Coating compositions comprising an aqueous film-forming polymer dispersion and a polyether silicon, preparation method thereof and use of same HEXION SPECIALTY CHEMICALS INC (US) 2009-04-15 CN claimed
CN-1989181-A Novel water-dispersible waterproofing agent, method for the production thereof and use thereof in the construction field and in particular in inorganic binder compositions RHONE POULENC CHIMIE (FR) 2007-06-27 CN claimed
CN-1890338-A Adhesion promoting agent for a thermal insulation surface HEXION SPECIALTY CHEMICALS INC (US) 2007-01-03 CN claimed
CN-1867728-A Product comprising a fibrous support and a hydrophilic and/or permeabilizing coating, method for the production thereof and use thereof RHONE POULENC CHIMIE (FR) 2006-11-22 CN claimed
CN-1863880-A Coating compositions comprising an aqueous film-forming polymer dispersion and a polyether silicon, preparation method thereof and use of same HEXION SPECIALTY CHEMICALS INC (US) 2006-11-15 CN claimed
CN-1726173-A Method for improving the water resistance of inorganic hydraulic binder compositions, compositions obtainable by this method and uses of these compositions RHONE POULENC CHIMIE (FR) 2006-01-25 CN claimed
CN-1187210-A Water redispersible power of film-forming polymers having a core/shell structure RHONE POULENC CHIMIE (FR) 1998-07-08 CN claimed
CN-102351481-A Method for enhancing the water repellency of inorganic hydraulic binder compositions and compositions obtainable by said method and their uses RHODIA CHIMIE SA 2012-02-15 CN disclosed
CN-1890338-B Adhesion promoting agent for a thermal insulation surface HEXION SPECIALTY CHEMICALS INC 2011-10-26 CN disclosed
CN-1989181-B Novel water-dispersible waterproofing agent, method for the production thereof and use thereof in the construction field and in particular in inorganic binder compositions RHONE POULENC CHIMIE 2011-08-24 CN disclosed
CN-100478409-C Coating compositions comprising an aqueous film-forming polymer dispersion and a polyether silicon, preparation method thereof and use of same HEXION SPECIALTY CHEMICALS INC (US) 2009-04-15 CN disclosed
CN-1989181-A Novel water-dispersible waterproofing agent, method for the production thereof and use thereof in the construction field and in particular in inorganic binder compositions RHONE POULENC CHIMIE (FR) 2007-06-27 CN disclosed
CN-1890338-A Adhesion promoting agent for a thermal insulation surface HEXION SPECIALTY CHEMICALS INC (US) 2007-01-03 CN disclosed
EP-0398576-B1 Multi-stage polymer particle having a hydrophobically-modified ionically soluble stage ROHM & HAAS (US) 1995-08-02 EP disclosed
CN-1090290-A Multi-stage polymers with caustic solubility and alkali insoluble stages ROHM & HAAS (US) 1994-08-03 CN disclosed
US-5266646-A Thickeners for waterbase paints; viscosity stabilizers to colorants; heat resistance; blister resistance; color float; syneresis resistance ROHM AND HAAS COMPANY (US) 1993-11-30 US disclosed
EP-0444791-A1 Polymeric thickeners for aqueous-based coatings ROHM AND HAAS COMPANY (US) 1991-09-04 EP disclosed
CN-1047322-A Multilayer polymeric composition granule with the improved ionically-soluble polymkeric substance of one deck hydrophobicity ROHM & HAAS (US) 1990-11-28 CN disclosed
US-4826997-A ADDITION POLYMERS THE DOW CHEMICAL COMPANY (US) 1989-05-02 US disclosed