Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887675 | 0.82 | CA2 (0.48) | CA2CA1ALDH1A1TSHRPOLB | |
| SCHEMBL7520146 | 0.80 | LMNA (0.55) | CA2CA1ALDH1A1TSHRPOLB | |
| SCHEMBL8763467 | 0.78 | CYP1A2 (0.48) | CA2CA1ALDH1A1TSHRPOLB | |
| SCHEMBL11364196 | 0.77 | KCNJ11 (0.57) | ALDH1A1POLBSMN1; SMN2TDP1KCNJ11 | |
| SCHEMBL16207643 | 0.76 | KDM4E (0.66) | ALDH1A1SMN1; SMN2TDP1CYP1A2CYP2C19 | |
| SCHEMBL11317791 | 0.76 | CYP2C19 (0.37) | ALDH1A1TSHRSMN1; SMN2TDP1KCNJ11 | |
| SCHEMBL9128005 | 0.76 | CA2 (0.42) | CA2CA1ALDH1A1TSHRPOLB | |
| SCHEMBL8772295 | 0.76 | HSPA5 (0.50) | CA2CA1ALDH1A1TSHRPOLB | |
| SCHEMBL9861935 | 0.76 | CA2 (0.42) | CA2CA1ALDH1A1TSHRPOLB | |
| SCHEMBL585863 | 0.74 | HTT (0.53) | CA2CA1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1745198-A | Method of preparing brominated hydroxy aromatic compounds | GEN ELECTRIC (US) | 2006-03-08 | — | — | CN | claimed |
| US-6827836-B2 | With high para selectivity; hydrogen bromide not generated as a by-product; | GENERAL ELECTRIC COMPANY | 2004-12-07 | — | — | US | claimed |
| WO-2004050954-A1 | METHOD OF PREPARING BROMINATED HYDROXY AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2004-06-17 | — | — | WO | claimed |
| US-20040104126-A1 | Method of preparing brominated hydroxy aromatic compounds | GENERAL ELECTRIC COMPANY | 2004-06-03 | — | — | US | claimed |
| CN-1745198-A | Method of preparing brominated hydroxy aromatic compounds | GEN ELECTRIC (US) | 2006-03-08 | — | — | CN | disclosed |
| US-6827836-B2 | With high para selectivity; hydrogen bromide not generated as a by-product; | GENERAL ELECTRIC COMPANY | 2004-12-07 | — | — | US | disclosed |
| WO-2004050954-A1 | METHOD OF PREPARING BROMINATED HYDROXY AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2004-06-17 | — | — | WO | disclosed |
| US-20040104126-A1 | Method of preparing brominated hydroxy aromatic compounds | GENERAL ELECTRIC COMPANY | 2004-06-03 | — | — | US | disclosed |