SCHEMBL887675

SCHEMBL887675

CC(C)(C)c1cc(C(C)(C)C)c2ccccc2c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 4/20 0.48
▸ CA1 P00915 2/20 0.48
▸ ALDH1A1 P00352 3/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ TSHR P16473 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ TYR P14679 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ GLRA3 O75311 1/20 0.45
▸ GLRB P48167 1/20 0.45
▸ ALOX5 P09917 2/20 0.43
▸ PTGS1 P23219 2/20 0.43
▸ PTGS2 P35354 2/20 0.43
▸ CYP1A2 P05177 3/20 0.42
▸ MAPT P10636 2/20 0.42
▸ ALOX15 P16050 2/20 0.42
▸ CYP2C9 P11712 2/20 0.42
▸ CYP2C19 P33261 2/20 0.42
▸ GABRA1 P14867 1/20 0.42
▸ GABRB2 P47870 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861935 0.88 CA2 (0.42) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL9861474 0.87 GLRA3 (0.43) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL7520146 0.85 LMNA (0.55) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL11499503 0.85 ALDH1A1 (0.50) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL8763467 0.83 CYP1A2 (0.48) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL6537313 0.82 CA2 (0.43) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL8772295 0.80 HSPA5 (0.50) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL9128005 0.80 CA2 (0.42) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL8762756 0.79 TP53 (0.50) CA2CA1ALDH1A1SMN1; SMN2TSHR
SCHEMBL8762782 0.79 HSPA5 (0.46) CA2CA1ALDH1A1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451184-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2019-10-22 — — US disclosed
EP-2949783-B1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR (JP) 2019-10-09 — — EP disclosed
EP-1666573-B1 LOW-FRICTION SLIDING MECHANISM AND METHOD OF FRICTION REDUCTION NISSAN MOTOR (JP) 2019-05-15 — — EP disclosed
EP-1508611-B1 TRANSMISSION COMPRISING LOW-FRICTION SLIDING MEMBERS AND TRANSMISSION OIL THEREFOR NISSAN MOTOR (JP) 2019-04-17 — — EP disclosed
EP-1510692-B1 Refrigerant compressor and friction control process therefor NISSAN MOTOR (JP) 2018-02-21 — — EP disclosed
US-20170335964-A1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR CO., LTD. (JP) 2017-11-23 — — US disclosed
US-9759323-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2017-09-12 — — US disclosed
EP-1666572-B1 SYSTEM HAVING DLC CONTACTING FACES, METHOD FOR LUBRICATING THE SYSTEM AND LUBRICATING OIL FOR THE SYSTEM NIPPON OIL CORP (JP) 2017-05-17 — — EP disclosed
EP-1953214-B1 Lubricant composition comprising a diamond nanoparticle NISSAN MOTOR (JP) 2016-09-14 — — EP disclosed
US-20150362072-A1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR CO., LTD. (JP) 2015-12-17 — — US disclosed
EP-1508611-A2 Low-friction sliding member in transmission, and transmission oil therefor NISSAN MOTOR COMPANY, LIMITED (JP) 2005-02-23 — — EP disclosed
EP-1507070-A1 Fuel lubricated sliding mechanism Nissan Motor Co., Ltd. (JP) 2005-02-16 — — EP disclosed
CN-1580539-A Fuel lubricated sliding mechanism NISSAN MOTOR (JP) 2005-02-16 — — CN disclosed
US-6838583-B2 Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and the methods of using the same WARNER-LAMBERT COMPANY LLC (US) 2005-01-04 — — US disclosed
EP-1409443-A2 NON-HALOGENATED NAPHTHOL COMPOUNDS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME WARNER-LAMBERT COMPANY (US) 2004-04-21 — — EP disclosed
US-20040010046-A1 Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same MCNEIL-PPC, INC 2004-01-15 — — US disclosed
US-20020110530-A1 Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same HARPER DAVID SCOTT (US) 2002-08-15 — — US disclosed
WO-2002050001-A2 NON-HALOGENATED NAPHTHOL COMPOUNDS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME WARNER-LAMBERT COMPANY (US) 2002-06-27 — — WO disclosed
US-4271059-A Color-developing composition for pressure-sensitive recording sheet material and process for the preparation thereof containing phenolic resin and hindered phenol MITSUI TOATSU CHEMICALS INC. (JP) 1981-06-02 — — US disclosed
US-4235769-A COPOLYMER OF P-ALKYLPHENOL, PHENOL AND FORMALDEHYDE, 6-(4-HYDROXY-3,5-DI-TERTBUTYLANILINO)-2,4-BIS(ALKYLTHIO)-S-TRIAZINES MITSUI TOATSU CHEMICALS, INC. (JP) 1980-11-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040010046-A1 Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same NPM1, NOC2L, NAF1 CA2 4571/4885CA1 4810/4885ALDH1A1 3207/4885
US-20020110530-A1 Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same NPM1, NOC2L, NAF1 CA2 4571/4885CA1 4810/4885ALDH1A1 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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