Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943127 | 0.84 | LMNA (0.37) | LMNA | |
| SCHEMBL28768318 | 0.79 | NOS3 (0.30) | — | |
| Carbamic Acid SCHEMBL6537377 | 0.79 | NOS3 (0.33) | — | |
| SCHEMBL126593 | 0.78 | CA12 (0.33) | LMNA | |
| SCHEMBL3223861 | 0.77 | BCHE (0.33) | LMNA | |
| SCHEMBL3212617 | 0.77 | MTNR1A (0.35) | LMNA | |
| SCHEMBL512341 | 0.77 | BCHE (0.32) | LMNA | |
| SCHEMBL9191906 | 0.77 | CA14 (0.37) | LMNA | |
| SCHEMBL16173583 | 0.75 | LMNA (0.31) | LMNA | |
| SCHEMBL19775775 | 0.75 | LMNA (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673954-B1 | REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST | GENERAL ELECTRIC COMPANY | 2004-01-06 | — | — | US | disclosed |