Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537758 | 0.84 | RECQL (0.44) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL6538199 | 0.81 | MAPT (0.52) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL11807535 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KCNMA1TDP1NPC1RAB9A | |
| SCHEMBL6537801 | 0.78 | AKR1C3 (0.53) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6537433 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL6537623 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TDP1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1704376 | 0.74 | ALDH1A1 (0.71) | ALDH1A1KCNMA1KDM4ENPC1RAB9A | |
| SCHEMBL10889343 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL11591034 | 0.71 | ALDH1A1 (0.67) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL2371809 | 0.71 | TSHR (0.60) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |