Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537433 | 0.82 | ALDH1A1 (0.47) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6537758 | 0.80 | RECQL (0.44) | SMN1; SMN2MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL6537526 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL7210379 | 0.77 | MAPT (0.49) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL7210382 | 0.77 | MAPT (0.49) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| Oxalic Acid SCHEMBL20984441 | 0.77 | AKR1C3 (0.60) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL3496332 | 0.76 | SMN1; SMN2 (0.66) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL3496338 | 0.76 | SMN1; SMN2 (0.66) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL8474164 | 0.73 | MAPT (0.59) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL6537797 | 0.73 | MAPT (0.59) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |