Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537801 | 0.82 | AKR1C3 (0.53) | ALDH1A1MAPK1MAPTLMNAMEN1 | |
| SCHEMBL6537758 | 0.79 | RECQL (0.44) | ALDH1A1L3MBTL1MAPK1TSHRMAPT | |
| SCHEMBL6537526 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1TSHRMAPT | |
| SCHEMBL6538199 | 0.74 | MAPT (0.52) | ALDH1A1MAPK1MAPTPKMLMNA | |
| SCHEMBL26125825 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1MAPK1TSHR | |
| SCHEMBL8524918 | 0.70 | MAPT (0.50) | ALDH1A1KDM4EL3MBTL1MAPK1TSHR | |
| SCHEMBL6537432 | 0.70 | MAPT (0.50) | ALDH1A1KDM4EL3MBTL1MAPK1TSHR | |
| SCHEMBL8611245 | 0.70 | MAPT (0.59) | ALDH1A1KDM4EL3MBTL1MAPK1TSHR | |
| SCHEMBL438853 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1MAPK1TSHR | |
| SCHEMBL438852 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |