Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537526 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1KCNMA1KMT2ANPC1 | |
| SCHEMBL6537758 | 0.76 | RECQL (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5606246 | 0.75 | KCNMA1 (0.64) | MAPTALDH1A1AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL31285866 | 0.74 | MAPT (0.55) | MAPTALDH1A1AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL6537433 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2APKM | |
| SCHEMBL11005634 | 0.74 | KCNMA1 (0.66) | MAPTALDH1A1AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL6538200 | 0.74 | MAPT (0.57) | MAPTALDH1A1AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL6538196 | 0.74 | MAPT (0.57) | MAPTALDH1A1AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL4490148 | 0.73 | MAPK1 (0.61) | MAPTALDH1A1AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL6537801 | 0.72 | AKR1C3 (0.53) | MAPTALDH1A1AKR1B1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |