Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Naphthalene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL626626 | 0.86 | CA9 (0.36) | TSHRCA12CA1CA3CA4 | |
| Biphenyl SCHEMBL847948 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1HPGDGAAMAPT | |
| Naphthalene SCHEMBL10590639 | 0.83 | CYP2A6 (0.61) | CYP2A6ALOX12TSHRCA12CA1 | |
| Naphthalene SCHEMBL7201843 | 0.83 | CYP2A6 (0.61) | CYP2A6ALOX12TSHRCA12CA1 | |
| Naphthalene SCHEMBL1478520 | 0.83 | CYP2A6 (0.61) | CYP2A6ALOX12TSHRCA12CA1 | |
| Naphthalene SCHEMBL3278833 | 0.83 | CYP2A6 (0.61) | CYP2A6ALOX12TSHRCA12CA1 | |
| Naphthalene SCHEMBL373901 | 0.83 | CYP2A6 (0.61) | CYP2A6ALOX12TSHRCA12CA1 | |
| Phenol SCHEMBL8733397 | 0.82 | TDP1 (0.55) | TSHRCA12CA1CA3CA4 | |
| Anthraquinone SCHEMBL9802630 | 0.80 | MEN1 (0.57) | CES2CES1POLBALDH1A1KDM4E | |
| Bicarbonate SCHEMBL726360 | 0.80 | TYMS (0.43) | TSHRCES2CES1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099751-B1 | ELECTROSTATIC INK COMPOSITIONS | HP INDIGO BV (NL) | 2018-12-12 | — | — | EP | claimed |
| EP-1745519-B1 | ORGANIC ELECTRONIC DEVICE | LG DISPLAY CO LTD (KR) | 2018-07-25 | — | — | EP | claimed |
| EP-2264097-B1 | Method for producing cure system, adhesive system, and electronic device | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-05-08 | — | — | EP | claimed |
| EP-1877483-B1 | METHOD FOR PRODUCING CURE SYSTEM, ADHESIVE SYSTEM, AND ELECTRONIC DEVICE | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-05-08 | — | — | EP | claimed |
| EP-1331234-B1 | Potting composition based on duroplastic epoxid resin | ABB RESEARCH LTD (CH) | 2004-09-22 | — | — | EP | claimed |
| EP-1331234-A1 | Potting composition based on duroplastic epoxid resin | ABB Research Ltd. (CH) | 2003-07-30 | — | — | EP | claimed |
| EP-1476881-A2 | DOPED ORGANIC SEMICONDUCTOR MATERIAL AND METHOD FOR PRODUCTION THEREOF | Novaled GmbH (DE) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003070822-A2 | DOPED ORGANIC SEMICONDUCTOR MATERIAL AND METHOD FOR PRODUCTION THEREOF | NOVALED GMBH (DE) | 2003-08-28 | — | — | WO | disclosed |