Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988750 | 0.89 | KDM4E (0.34) | ALDH1A1EPHX2KDM4EL3MBTL1 | |
| SCHEMBL2982384 | 0.83 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL2988042 | 0.83 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL2015392 | 0.68 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL2015391 | 0.68 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL6757690 | 0.66 | CRBN (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL6757693 | 0.66 | CRBN (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL9247017 | 0.65 | CA1 (0.39) | ALDH1A1 | |
| SCHEMBL29328920 | 0.65 | CRBN (0.33) | ALDH1A1 | |
| SCHEMBL28962321 | 0.65 | ALDH1A1 (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040073033-A1 | Process for the preparation of phenylalanine enamide derivatives | UCB PHARMA S.A. (BE) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073033-A1 | Process for the preparation of phenylalanine enamide derivatives | NPY2R, NPY1R, NPR1 | ALDH1A1 1396/4885EPHX2 470/4885KDM4E 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.