Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986523 | 0.88 | LMNA (0.47) | SLC6A3SLC6A4ALDH1A1KDM4ETSHR | |
| SCHEMBL562324 | 0.81 | LMNA (0.40) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL31710278 | 0.81 | LMNA (0.44) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL29627829 | 0.80 | SLC6A4 (0.39) | SLC6A3SLC6A4ALDH1A1KDM4ETSHR | |
| SCHEMBL1526822 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL25245488 | 0.80 | TSHR (0.39) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL17442464 | 0.80 | LMNA (0.39) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL17939979 | 0.80 | SLC6A4 (0.39) | SLC6A3SLC6A4ALDH1A1KDM4ETSHR | |
| SCHEMBL19923134 | 0.80 | PDK2 (0.40) | SLC6A3SLC6A4ALDH1A1KDM4ETSHR | |
| SCHEMBL20232183 | 0.79 | LPL (0.48) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006143-A1 | For therapy of urinary incontinence | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006143-A1 | For therapy of urinary incontinence | H1-0, HRH2, H1-2 | SLC6A3 1710/4885SLC6A4 1621/4885ALDH1A1 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.