Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539214 | 1.00 | ADRB1 (0.54) | ADRB1ADRB3ADRB2GAAKMT2A | |
| SCHEMBL6538684 | 0.93 | ADRB1 (0.44) | ADRB1ADRB3ADRB2KMT2AMEN1 | |
| SCHEMBL6539338 | 0.80 | ADRB1 (0.39) | ADRB1ADRB3ADRB2ALDH1A1PPIA | |
| SCHEMBL6539708 | 0.69 | ADRB3 (0.36) | ADRB3 | |
| SCHEMBL6538469 | 0.68 | MEN1 (0.47) | ADRB1ADRB3KMT2AMEN1MAPT | |
| SCHEMBL6538564 | 0.68 | ADRB3 (0.55) | ADRB1ADRB3ADRB2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL6539793 | 0.67 | ADRB3 (0.92) | ADRB1ADRB3ADRB2KMT2AMEN1 | |
| SCHEMBL4106750 | 0.67 | MEN1 (0.68) | GAAKMT2AMEN1ALDH1A1BAZ1A | |
| SCHEMBL6539299 | 0.67 | ADRB3 (0.57) | ADRB1ADRB3ADRB2KMT2AMEN1 | |
| SCHEMBL6129390 | 0.66 | MEN1 (0.90) | GAAKMT2AMEN1ALDH1A1BAZ1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |