Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539338 | 0.81 | ADRB1 (0.39) | ADRB3 | |
| SCHEMBL6540224 | 0.78 | BACE1 (0.43) | ADRB3BACE1 | |
| SCHEMBL6538543 | 0.78 | BACE1 (0.43) | ADRB3BACE1 | |
| SCHEMBL18651963 | 0.77 | ALOX5 (0.36) | ADRB3BACE1MAOBALOX5 | |
| SCHEMBL6539595 | 0.72 | MAPT (0.48) | ADRB3 | |
| SCHEMBL6539353 | 0.70 | ADRB1 (0.42) | ADRB3BACE1 | |
| SCHEMBL6538469 | 0.70 | MEN1 (0.47) | ADRB3BACE1 | |
| SCHEMBL6539211 | 0.69 | ADRB1 (0.54) | ADRB3 | |
| SCHEMBL20083645 | 0.69 | BACE1 (0.36) | ADRB3BACE1 | |
| SCHEMBL7120714 | 0.68 | ADRB3 (0.49) | ADRB3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |