Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.40 |
| ▸ | PPIF | P30405 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MYOC | Q99972 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539214 | 0.93 | ADRB1 (0.54) | ADRB1ADRB3MAPK1ALDH1A1PKM | |
| SCHEMBL6539211 | 0.93 | ADRB1 (0.54) | ADRB1ADRB3MAPK1ALDH1A1PKM | |
| SCHEMBL6539338 | 0.83 | ADRB1 (0.39) | ADRB1ADRB3MAPK1ALDH1A1ADRB2 | |
| SCHEMBL6539708 | 0.72 | ADRB3 (0.36) | ADRB3 | |
| SCHEMBL6539595 | 0.67 | MAPT (0.48) | ADRB1ADRB3ALDH1A1MAPTADRB2 | |
| SCHEMBL6538911 | 0.66 | ADRB3 (0.56) | ADRB1ADRB3MEN1KMT2AMAPT | |
| SCHEMBL6539156 | 0.66 | ADRB1 (0.53) | ADRB1ADRB3MAPTADRB2 | |
| SCHEMBL6539710 | 0.66 | ADRB1 (0.53) | ADRB1ADRB3MEN1KMT2AMAPT | |
| Trifluoroacetic Acid SCHEMBL6539290 | 0.65 | ADRB3 (0.79) | ADRB1ADRB3MAPK1ALDH1A1PKM | |
| SCHEMBL6539510 | 0.64 | ADRB1 (0.59) | ADRB1ADRB3MAPTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |