Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538330 | 0.90 | POLB (0.39) | ALDH1A1KDM4EHPGDGLAPOLB | |
| SCHEMBL9258457 | 0.75 | LMNA (0.50) | ALDH1A1KDM4EHTTLMNAL3MBTL1 | |
| SCHEMBL29029672 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1POLBMAPTL3MBTL1MEN1 | |
| SCHEMBL6133369 | 0.73 | LMNA (0.39) | ALDH1A1KDM4EHPGDGLAPOLB | |
| SCHEMBL5150644 | 0.73 | POLB (0.40) | ALDH1A1KDM4EHPGDGLAPOLB | |
| SCHEMBL5388545 | 0.73 | LMNA (0.39) | ALDH1A1KDM4EHPGDGLAPOLB | |
| SCHEMBL6923211 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDGLAPOLB | |
| SCHEMBL7708924 | 0.70 | SMN1; SMN2 (0.44) | ALDH1A1HTTMAPTL3MBTL1MEN1 | |
| SCHEMBL29029675 | 0.70 | SMN1; SMN2 (0.44) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL27496358 | 0.70 | SMN1; SMN2 (0.47) | ALDH1A1POLBMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | ADORA1, ADORA2A, P2RX5 | ALDH1A1 1399/4885KDM4E 3052/4885HPGD 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.