Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388545 | 0.80 | LMNA (0.39) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL5150644 | 0.80 | POLB (0.40) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL6133369 | 0.80 | LMNA (0.39) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL5152700 | 0.76 | TP53 (0.38) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL5796382 | 0.73 | MMP2 (0.40) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5147972 | 0.71 | GPR139 (0.39) | ALDH1A1KDM4EHPGDGLAMAPT | |
| SCHEMBL5152357 | 0.70 | CES2 (0.43) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL27679545 | 0.69 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL5147931 | 0.68 | POLB (0.44) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL5149065 | 0.68 | ADORA2A (0.34) | ALDH1A1LMNAPOLBHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089939-A1 | CONDENSED FURAN DERIVATIVES AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-21 | — | — | WO | disclosed |