SCHEMBL6539289

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5259104	0.78	CYP1A2 (0.64)	CYP1A2PTGS1AKR1B1PDE3BPDE3A
	SCHEMBL10354174	0.78	CYP1A2 (0.67)	CYP1A2AKR1B1PDE3BPDE3AHPGD
	SCHEMBL11242504	0.76	LMNA (0.49)	CYP1A2AKR1B1PDE3BPDE3AMEN1
	SCHEMBL482059	0.76	CYP1A2 (1.00)	CYP1A2AKR1B1PDE3BPDE3AHPGD
	SCHEMBL7689907	0.75	CYP1A2 (0.96)	CYP1A2AKR1B1PDE3BPDE3AHPGD
	SCHEMBL6133302	0.74	CYP1A2 (0.54)	CYP1A2KMT2AGPR119
	SCHEMBL21692150	0.74	PTGS1 (0.58)	PTGS1PTGS2MEN1KMT2AALDH1A1
	SCHEMBL26570373	0.73	KDM4E (0.50)	CYP1A2PTGS1PTGS2HPGDMEN1
	SCHEMBL37278	0.72	PTGS2 (0.66)	PTGS1PTGS2HPGDMEN1KMT2A
	SCHEMBL12854120	0.72	PTPRC (0.57)	PTGS1PTGS2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.