Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.54 |
| ▸ | NPC1 | O15118 | 11/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6540012 | 0.83 | ADRB1 (0.62) | RAB9ANPC1HPGDSMN1; SMN2NFKB1 | |
| SCHEMBL6538630 | 0.79 | ADRB1 (0.43) | POLBMAPTADRB1ADRB3 | |
| SCHEMBL6539444 | 0.79 | KMT2A (0.52) | ALDH1A1ADRB1ADRB3 | |
| SCHEMBL6539311 | 0.79 | ADRB1 (0.45) | MAPTADRB1ADRB3 | |
| SCHEMBL6539459 | 0.78 | NPC1 (0.46) | RAB9ANPC1POLBALDH1A1ADRB1 | |
| SCHEMBL6539620 | 0.77 | ADRB1 (0.46) | RAB9ANPC1MAPTADRB1ADRB3 | |
| SCHEMBL6538847 | 0.77 | ADRB1 (0.48) | RAB9ANPC1MAPTADRB1ADRB3 | |
| SCHEMBL6539710 | 0.77 | ADRB1 (0.53) | RAB9ANPC1MAPTADRB1ADRB3 | |
| SCHEMBL6538911 | 0.76 | ADRB3 (0.56) | RAB9ANPC1POLBMAPTADRB1 | |
| SCHEMBL6539156 | 0.75 | ADRB1 (0.53) | MAPTADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |