Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539444 | 0.88 | KMT2A (0.52) | ADRB1ADRB3ALDH1A1KMT2AITGB1 | |
| Hydrochloric Acid SCHEMBL6538979 | 0.82 | ADRB3 (0.65) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL6539620 | 0.79 | ADRB1 (0.46) | NPC1RAB9AADRB1ADRB3MEN1 | |
| SCHEMBL6538847 | 0.79 | ADRB1 (0.48) | NPC1RAB9AADRB1ADRB3MEN1 | |
| SCHEMBL6539601 | 0.78 | RAB9A (0.54) | NPC1RAB9AADRB1ADRB3ALDH1A1 | |
| SCHEMBL6542153 | 0.78 | MEN1 (0.48) | NPC1RAB9AADRB1ADRB3MEN1 | |
| SCHEMBL6542157 | 0.78 | MEN1 (0.48) | NPC1RAB9AADRB1ADRB3MEN1 | |
| SCHEMBL6538911 | 0.78 | ADRB3 (0.56) | NPC1RAB9AADRB1ADRB3MEN1 | |
| SCHEMBL6538630 | 0.78 | ADRB1 (0.43) | ADRB1ADRB3POLBNPSR1 | |
| SCHEMBL6538698 | 0.77 | NPC1 (0.43) | NPC1RAB9AADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |