Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 10/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539311 | 0.83 | ADRB1 (0.45) | ADRB1ADRB3MAPT | |
| Hydrochloric Acid SCHEMBL7558333 | 0.82 | ADRB3 (0.64) | ADRB1ADRB3MAPTLMNAL3MBTL1 | |
| SCHEMBL6538847 | 0.80 | ADRB1 (0.48) | ADRB1ADRB3MAPTLMNA | |
| SCHEMBL6539601 | 0.79 | RAB9A (0.54) | ADRB1ADRB3MAPTPOLB | |
| SCHEMBL6539444 | 0.79 | KMT2A (0.52) | ADRB1ADRB3 | |
| SCHEMBL6539620 | 0.78 | ADRB1 (0.46) | ADRB1ADRB3MAPT | |
| SCHEMBL6539710 | 0.78 | ADRB1 (0.53) | ADRB1ADRB3MAPT | |
| SCHEMBL6539459 | 0.78 | NPC1 (0.46) | ADRB1ADRB3POLBNPSR1 | |
| SCHEMBL6538911 | 0.78 | ADRB3 (0.56) | ADRB1ADRB3MAPTPOLB | |
| SCHEMBL6539156 | 0.76 | ADRB1 (0.53) | ADRB1ADRB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |