SCHEMBL65400

SCHEMBL65400

C=C(C)C(=O)Oc1cc2c(cc1C(=O)O)C(=O)OC2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.39
CA7 P43166 5/20 0.39
CA1 P00915 4/20 0.39
ELANE P08246 1/20 0.38
CFD P00746 2/20 0.37
KDM4E B2RXH2 5/20 0.36
HSD17B10 Q99714 4/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
PTGS1 P23219 2/20 0.36
PTGS2 P35354 2/20 0.36
TSHR P16473 2/20 0.36
CA2 P00918 2/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36
GGT1 P19440 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252339 0.86 CFD (0.51) CA12CA7CA1CFDKDM4E
SCHEMBL65777 0.79 CFD (0.44) ELANECFDKDM4EHSD17B10ALDH1A1
SCHEMBL2059843 0.77 CA2 (0.36) CA12CA7CA1ALDH1A1TSHR
SCHEMBL64565 0.76 THRB (0.39) CA12CA7CA1ALDH1A1TSHR
SCHEMBL540750 0.74 TYMS (0.50) CA12CA7CA1KDM4EHSD17B10
SCHEMBL17717380 0.74 ELANE (0.49) CA12ELANEKDM4EALDH1A1CA2
SCHEMBL2059836 0.73 POLB (0.41) CA12CA7CA1TSHRCA2
SCHEMBL16978017 0.72 THRB (0.42) CA1KDM4EHSD17B10ALDH1A1HPGD
SCHEMBL11908091 0.71 ELANE (0.39) CA7CA1ELANEKDM4EALDH1A1
SCHEMBL344654 0.70 KDM4E (0.70) ELANECFDKDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116288767-A High-elasticity high-temperature-resistant spandex fiber and preparation method thereof 诸暨华海氨纶有限公司 2023-06-23 CN claimed
CN-112336634-B Dentin adhesion pretreatment composition based on microenvironment-induced nanoparticle redeposition and application 浙江大学 2022-03-22 CN claimed
CN-112494340-B Dental bonding pretreatment material and application 浙江大学 2021-12-10 CN claimed
CN-113304054-A Dental self-acid-etching adhesive with remineralization effect and preparation method thereof 陕西恒远生物科技有限公司 2021-08-27 CN claimed
CN-112494340-A Dental bonding pretreatment material and application 浙江大学 2021-03-16 CN claimed
CN-108143634-B Dental root surface protection material composition 北京安泰生物医用材料有限公司 2021-02-19 CN claimed
CN-112336634-A Dentin adhesion pretreatment composition based on microenvironment-induced nanoparticle redeposition and application 浙江大学 2021-02-09 CN claimed
US-5876743-A ADHESION OF BONE TO PROSTHETIC DEN-MAT CORPORATION (US) 1999-03-02 US claimed
CN-117959489-A Novel bone material substitution synthesis formula, preparation method and use method 薪创生命科技有限公司 2024-05-03 CN disclosed
CN-116766720-B Plastic film based on laser technology and preparation process thereof 上海人民塑料印刷厂有限公司 2024-03-26 CN disclosed
CN-117467315-B Fluorocarbon weather-resistant resin powder coating and preparation method thereof 佛山市鑫诚环保新材料有限公司 2024-03-15 CN disclosed
CN-117467315-A Fluorocarbon weather-resistant resin powder coating and preparation method thereof 佛山市鑫诚环保新材料有限公司 2024-01-30 CN disclosed
CN-117089054-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-11-21 CN disclosed
CN-116766720-A Plastic film based on laser technology and preparation process thereof 上海人民塑料印刷厂有限公司 2023-09-19 CN disclosed
EP-1027877-B1 TOOTH COATING COMPOSITION KAO CORP (JP) 2007-11-14 EP disclosed
US-20050123762-A1 Polymerizable composition, cured object obtained therefrom, and composite material SUN MEDICAL CO., LTD. (JP) 2005-06-09 US disclosed
US-6491898-B1 ACRYLIC POLYMER FILMS HAVING MODERATE BONDING STRENGTH AND SPECIFIC SOLUBILITY IN WATER AND ETHANOL KAO CORPORATION (JP) 2002-12-10 US disclosed
US-6420504-B1 POLYSILOXANES DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-07-16 US disclosed
EP-1055674-A1 BRANCHED SILOXANE/SILALKYLENE COPOLYMER, SILICONE-CONTAINING ORGANIC POLYMER, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Silicone Company, Ltd. (JP) 2000-11-29 EP disclosed
EP-1027877-A1 TOOTH COATING COMPOSITION Kao Corporation (JP) 2000-08-16 EP disclosed