SCHEMBL64565

SCHEMBL64565

C=C(C)C(=O)OCCc1cc2c(cc1C(=O)O)C(=O)OC2=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 3/20 0.35
CA1 P00915 5/20 0.33
CA12 O43570 5/20 0.33
CA7 P43166 5/20 0.33
CA2 P00918 3/20 0.33
CA4 P22748 2/20 0.32
TYMS P04818 1/20 0.32
ALDH1A1 P00352 3/20 0.31
GLA P06280 1/20 0.31
KMT2A Q03164 1/20 0.31
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059836 0.94 POLB (0.41) THRBPOLBAPEX1HTTTDP1
SCHEMBL6544427 0.88 POLB (0.41) THRBPOLBAPEX1HTTTDP1
SCHEMBL2059843 0.88 CA2 (0.36) THRBPOLBAPEX1HTTTDP1
SCHEMBL16978017 0.83 THRB (0.42) THRBPOLBAPEX1HTTTDP1
SCHEMBL33455 0.83 THRB (0.45) THRBPOLBAPEX1HTTTDP1
SCHEMBL242494 0.80 HTT (0.41) THRBPOLBAPEX1HTTTDP1
SCHEMBL3266665 0.80 THRB (0.44) THRBTSHRCA1CA12CA7
SCHEMBL16978020 0.79 THRB (0.39) THRBPOLBAPEX1HTTTDP1
SCHEMBL20107566 0.78 THRB (0.40) THRBPOLBAPEX1HTTTDP1
SCHEMBL28637422 0.78 POLB (0.38) THRBPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1646 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL KULZER GMBH (DE) 2024-06-20 US claimed
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT SHOFU INC. (JP) 2024-05-30 US claimed
CN-118085771-A BIPV (building integrated photovoltaic) bottom plate building material glue and preparation method and application thereof 上海品诚控股集团有限公司 2024-05-28 CN claimed
US-20240158614-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY IVOCLAR VIVADENT AG (LI) 2024-05-16 US claimed
EP-4356893-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY Ivoclar Vivadent AG (LI) 2024-04-24 EP claimed
CN-117898949-A Enzyme-resistant nano molecular sieve composite material and application thereof 吉林大学 2024-04-19 CN claimed
CN-117898950-A Improved bonding system and application thereof 吉林大学 2024-04-19 CN claimed
CN-117844332-A High-flash-point low-VOC silver powder enamel and preparation method thereof 浙江天女集团制漆有限公司 2024-04-09 CN claimed
CN-117695158-A Biological ceramic coating, gutta-percha point and preparation method thereof 朗力生物医药(武汉)有限公司 2024-03-15 CN claimed
EP-4321145-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT Shofu Inc. (JP) 2024-02-14 EP claimed
EP-0252603-A2 Adhesives for ceramics and processes for the bonding of ceramics using same MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-01-13 EP claimed
US-4659751-A Simplified method for obtained strong adhesive bonding of composites to dentin, enamel and other substrates AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1987-04-21 US claimed
US-4588756-A Multi-step method for obtaining strong adhesive bonding of composites to dentin, enamel and other substrates AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1986-05-13 US claimed
EP-0151612-A1 IMPROVING THE ADHESION OF COMPOSITES TO DENTIN, ENAMEL AND OTHER SUBSTRATES. AMERICAN DENTAL ASS (US) 1985-08-21 EP claimed
US-4521550-A Method for obtaining strong adhesive bonding of composites to dentin, enamel and other substrates AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1985-06-04 US claimed
US-4514527-A TREATING WITH AQUEOUS SOLUTION OF CARBOXY-CONTAINING SALT AND HAVING AN OXIDIZABLE CATION AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1985-04-30 US claimed
WO-1985000514-A1 IMPROVING THE ADHESION OF COMPOSITES TO DENTIN, ENAMEL AND OTHER SUBSTRATES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1985-02-14 WO claimed
EP-0023321-B1 COMPOSITE FILLER AND DENTAL COMPOSITION CONTAINING THE SAME MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-02-06 EP claimed
EP-0023321-A2 Composite filler and dental composition containing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-02-04 EP claimed
US-4148988-A DENTAL ADHESIVE AND UNDERVOATING FOR PAINTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1979-04-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL CAD, MTHFD2, MAT2B THRB 344/4885POLB 1544/4885APEX1 243/4885
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT GRIK1, GRIN2B, GRIK2 THRB 599/4885POLB 1327/4885APEX1 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.