Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6553108 | 0.80 | ADRB3 (0.45) | ADRB3ADRB1ADRB2CYP19A1ALOX5 | |
| SCHEMBL6540079 | 0.80 | ADRB3 (0.53) | ADRB3ADRB1KDM4ECYP3A4MAPT | |
| SCHEMBL6540084 | 0.80 | ADRB3 (0.53) | ADRB3ADRB1KDM4ECYP3A4MAPT | |
| SCHEMBL5375729 | 0.79 | ADRB2 (0.50) | ADRB3ADRB1KDM4ECYP3A4MAPT | |
| SCHEMBL6552488 | 0.77 | TAS2R14 (0.46) | TAS2R14OPRK1OPRM1LPAR1LPAR5 | |
| SCHEMBL6554335 | 0.75 | L3MBTL1 (0.46) | TAS2R14TP53MAPTTSHR | |
| SCHEMBL4608624 | 0.74 | ADRB2 (0.47) | ADRB3ADRB1KDM4EMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL6540571 | 0.72 | ADRB3 (0.61) | ADRB3ADRB1KDM4ECYP3A4MAPT | |
| SCHEMBL4606845 | 0.71 | ADRB2 (0.42) | ADRB3ADRB1KDM4EMAPTTDP1 | |
| SCHEMBL6539213 | 0.68 | ADRB3 (0.51) | ADRB3ADRB1MAPTTSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |