Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.69 |
| ▸ | HTR6 | P50406 | 5/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42400 | 0.82 | TAAR1 (1.00) | TAAR1MAOBAOC3CHRM2CHRM1 | |
| SCHEMBL3151230 | 0.82 | MTNR1B (0.56) | HTR6MTNR1BCA1CA2CA9 | |
| SCHEMBL31352975 | 0.82 | MTNR1B (0.56) | HTR6MTNR1BCA1CA2CA9 | |
| SCHEMBL6679665 | 0.82 | HTR6 (0.51) | TAAR1HTR6MAOBTAS2R14MTNR1B | |
| Ammonia Solution, Strong SCHEMBL28996261 | 0.81 | TAAR1 (0.96) | TAAR1MAOBAOC3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL10917318 | 0.81 | TAAR1 (0.96) | TAAR1MAOBAOC3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL19950932 | 0.79 | TAAR1 (0.93) | TAAR1MAOBAOC3CHRM2CHRM1 | |
| SCHEMBL6540194 | 0.79 | BCHE (0.61) | HTR6TAS2R14CHRM2CHRM1CHRM3 | |
| SCHEMBL8865965 | 0.78 | LMNA (0.56) | HTR6MTNR1BCA1CA2CA9 | |
| SCHEMBL14282636 | 0.77 | PGR (0.56) | HTR6TAS2R14MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | TAAR1 201/4885HTR6 522/4885MAOB 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.