Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697927 | 1.00 | S1PR1 (0.45) | S1PR1GRM4ENPP2TNFGSK3B | |
| SCHEMBL6481575 | 1.00 | S1PR1 (0.45) | S1PR1GRM4ENPP2TNFGSK3B | |
| SCHEMBL8949484 | 0.85 | GSK3B (0.49) | S1PR1GRM4ENPP2TNFGSK3B | |
| SCHEMBL9646909 | 0.84 | LMNA (0.52) | S1PR1GRM4ENPP2TNFGSK3B | |
| SCHEMBL16961857 | 0.81 | S1PR1 (0.45) | S1PR1GRM4ENPP2TNFGSK3B | |
| SCHEMBL29256492 | 0.81 | TSHR (0.38) | CYP3A4TSHR | |
| SCHEMBL30988804 | 0.81 | TSHR (0.38) | CYP3A4TSHR | |
| SCHEMBL12056784 | 0.81 | GRM4 (0.44) | S1PR1GRM4ENPP2TNFGSK3B | |
| SCHEMBL25933186 | 0.81 | GLA (0.42) | S1PR1GRM4ENPP2TNFGSK3B | |
| SCHEMBL4693798 | 0.80 | ENPP2 (0.48) | S1PR1GRM4ENPP2TNFGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | S1PR1 780/4885GRM4 3766/4885ENPP2 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.