SCHEMBL6541794

SCHEMBL6541794

C[C@H](Cc1ccc(S(=O)(=O)c2ccc(OCC(=O)O)c(F)c2)cc1)NC(=O)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
FFAR1 O14842 8/20 0.40
PTGDR2 Q9Y5Y4 5/20 0.40
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
PPARA Q07869 2/20 0.39
PTGDR Q13258 1/20 0.39
ACACB O00763 1/20 0.39
NAMPT P43490 2/20 0.39
ALDH1A1 P00352 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6541355 0.90 PTPN1 (0.46) PTPN1PTGDR2PPARGPPARDPPARA
SCHEMBL6539930 0.89 PTPN1 (0.45) PTPN1PTGDR2ALDH1A1
SCHEMBL6540840 0.88 NAMPT (0.45) ACACBNAMPTCNR1
SCHEMBL6541730 0.87 CNR1 (0.38) ACACBNAMPTCNR1
SCHEMBL6552876 0.86 ESR1 (0.39) ACACBNAMPTCNR1
SCHEMBL6540798 0.86 ALDH1A1 (0.56) ACACBALDH1A1CNR1
SCHEMBL6541394 0.84 ABCC9 (0.44) ACACBNAMPTALDH1A1CNR1
SCHEMBL6552874 0.84 ESR1 (0.38) ACACBNAMPTCNR1
SCHEMBL6540415 0.82 CNR1 (0.40) ACACBALDH1A1CNR1
SCHEMBL6540375 0.82 PTPN1 (0.45) PTPN1FFAR1PTGDR2PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040138462-A1 Aminoalcohol derivatives ASTELLAS PHARMA INC. (JP) 2004-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040138462-A1 Aminoalcohol derivatives BPHL, FANCD2, HRH2 PTPN1 4443/4885FFAR1 282/4885PTGDR2 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.