Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17221770 | 0.75 | MGLL (0.41) | CA1CA2TSHR | |
| SCHEMBL13360086 | 0.74 | SRD5A2 (0.57) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL18077481 | 0.73 | SRD5A2 (0.65) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL9545841 | 0.73 | PIN1 (0.36) | TSHRCYP1A2 | |
| Water SCHEMBL28711864 | 0.72 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| Water SCHEMBL2565838 | 0.70 | SRD5A2 (0.80) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL1635858 | 0.69 | SRD5A2 (0.65) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL11772204 | 0.69 | SRD5A2 (0.65) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL71433 | 0.69 | SRD5A2 (0.65) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL36693 | 0.69 | SRD5A2 (0.87) | SRD5A2RARBRARGNR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730242-B2 | EFFICIENCY | THE UNIVERSITY OF ROCHESTER | 2004-05-04 | — | — | US | disclosed |
| US-20030164473-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2003-09-04 | — | — | US | disclosed |
| US-6558572-B2 | Optical device | UNIVERSITY OF ROCHESTER | 2003-05-06 | — | — | US | disclosed |
| US-20010036517-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2001-11-01 | — | — | US | disclosed |