Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.37 |
| ▸ | RARG | P13631 | 4/20 | 0.37 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.35 |
| ▸ | GLRB | P48167 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | RXRB | P28702 | 4/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989103 | 0.76 | ALDH1A1 (0.41) | RXRARXRBRXRGNR1H4 | |
| Hydrochloric Acid SCHEMBL7945358 | 0.76 | TDP1 (0.44) | TDP1RARBRARGRXRARXRB | |
| SCHEMBL3637333 | 0.74 | TNFRSF1A (0.56) | RARBRARGRARATNFRSF1AGLRA3 | |
| SCHEMBL9623299 | 0.71 | PLAU (0.45) | RARBRARGRARATNFRSF1AGLRA3 | |
| SCHEMBL9396541 | 0.71 | TSHR (0.44) | RARBRARGRARATNFRSF1AGLRA3 | |
| SCHEMBL8302162 | 0.71 | TNFRSF1A (0.47) | RARBRARGRARATNFRSF1AGLRA3 | |
| SCHEMBL7792646 | 0.70 | TSHR (0.42) | RARGTNFRSF1ARXRARXRBRXRG | |
| SCHEMBL11659614 | 0.70 | GLRA3 (0.47) | TNFRSF1AGLRA3GLRB | |
| SCHEMBL7924691 | 0.70 | RXRA (0.40) | RARBRARGRARARXRARXRB | |
| SCHEMBL7792403 | 0.69 | TNFRSF1A (0.48) | TDP1RARBRARGRARATNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730242-B2 | EFFICIENCY | THE UNIVERSITY OF ROCHESTER | 2004-05-04 | — | — | US | disclosed |
| US-20030164473-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2003-09-04 | — | — | US | disclosed |
| US-6558572-B2 | Optical device | UNIVERSITY OF ROCHESTER | 2003-05-06 | — | — | US | disclosed |
| US-20010036517-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2001-11-01 | — | — | US | disclosed |