SCHEMBL654480

SCHEMBL654480

[C]1=CCc2ccccc2OS1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
OXTR P30559 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.30
ITGB2 P05107 1/20 0.30
ICAM1 P05362 1/20 0.30
ITGAL P20701 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3995657 0.71 MAOA (0.38) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL3078 0.70 MAOA (0.41) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL9116473 0.68 MAOA (0.35) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL217973 0.67
SCHEMBL1724509 0.67 MAOA (0.42) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL231836 0.67 MAOA (0.38) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL4513967 0.65 MAOA (0.37) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL1747875 0.65 MAOA (0.37) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL2873 0.64 RYR2 (0.31)
SCHEMBL375376 0.64 MAOA (0.39) MAOAMAOBOXTRABCG2ITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240231224-A9 HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF LAM RESEARCH CORPORATION 2024-07-11 US disclosed
WO-2024137876-A2 SURFACE MODIFICATION OF METAL CATALYSTS WITH HYDROPHOBIC LIGANDS OR IONOMERS TWELVE BENEFIT CORPORATION (US) 2024-06-27 WO disclosed
US-20240200208-A1 CO2 PURIFICATION AND REDUCTION SYSTEMS SUMITOMO MITSUI BANKING CORPORATION 2024-06-20 US disclosed
WO-2024123514-A1 CO2 PURIFICATION AND REDUCTION SYSTEMS TWELVE BENEFIT CORPORATION (US) 2024-06-13 WO disclosed
US-20240192590-A1 APPARATUS AND PROCESS FOR EUV DRY RESIST SENSITIZATION BY GAS PHASE INFUSION OF A SENSITIZER LAM RESEARCH CORPORATION 2024-06-13 US disclosed
CN-118159909-A Gray tone resist and processing 元平台技术有限公司 2024-06-07 CN disclosed
WO-2024108304-A1 DITHIOL CHELATORS FOR METAL CONJUGATION TO ANTIBODIES STANDARD BIOTOOLS CANADA INC. (CA) 2024-05-30 WO disclosed
US-20240134274-A1 HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF LAM RES CORP (US) 2024-04-25 US disclosed
WO-2024081174-A1 OXYMETHYLENE COPOLYMERS FOR TRANSIENT SURFACE PROTECTION DURING CHEMICAL VAPOR DEPOSITION LAM RESEARCH CORPORATION (US) 2024-04-18 WO disclosed
WO-2024081263-A1 DEPOSITION OF METAL-CONTAINING FILMS LAM RESEARCH CORPORATION (US) 2024-04-18 WO disclosed
EP-1577282-A2 Metal complexes for use in olefin methathesis and atom or group transfer reactions Universiteit Gent (BE) 2005-09-21 EP disclosed
WO-2005082819-A2 METAL COMPLEXES FOR USE IN OLEFIN METATHESIS AND ATOM GROUP TRANSFER REACTIONS UNIVERSITEIT GENT (BE) 2005-09-09 WO disclosed
US-20050159581-A1 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same LIMBURGS UNIVERSITAIR CENTRUM (BE) 2005-07-21 US disclosed
EP-1548044-A2 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM VZW (BE) 2005-06-29 EP disclosed
EP-1529794-A1 Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM VZW (BE) 2005-05-11 EP disclosed
WO-2005039587-A1 HETEROCYCLE-SUBSTITUTED PTERIDINE DERIVATIVES AND THEIR USE IN THERAPY 4 AZA BIOSCIENCE NV (BE) 2005-05-06 WO disclosed
WO-2005035121-A2 SCHIFF BASE METAL COMPLEXES FOR USE AS CATALYSTS IN ORGANIC SYNTHESIS UNIVERSITEIT GENT (BE) 2005-04-21 WO disclosed
US-20050043541-A1 Metal complexes useful in metathesis and other reactions RIMTEC CORPORATION (JP) 2005-02-24 US disclosed
WO-2004104005-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA BIOSCIENCE NV (BE) 2004-12-02 WO disclosed
EP-1479682-A1 Immunosuppressive effects of pteridine derivatives 4 AZA Bioscience nv (BE) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043541-A1 Metal complexes useful in metathesis and other reactions TST, ETFA, TTPA MAOA 9/4885MAOB 126/4885OXTR 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.