Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026557 | 0.85 | SMN1; SMN2 (0.49) | ACHEBCHEPKMMAPTKMT2A | |
| SCHEMBL28026558 | 0.85 | SMN1; SMN2 (0.49) | ACHEBCHEPKMMAPTKMT2A | |
| SCHEMBL26108929 | 0.78 | ALDH1A1 (0.44) | MAPTKMT2APOLBMMP1MMP2 | |
| SCHEMBL6802675 | 0.75 | MAPT (0.46) | ACHEBCHEPKMHSD17B10MAPT | |
| SCHEMBL27175576 | 0.75 | F2 (0.42) | MAPTKMT2AMMP1MMP2MMP9 | |
| SCHEMBL7372959 | 0.75 | ALDH1A1 (0.45) | ACHEBCHEKMT2AMEN1MMP1 | |
| SCHEMBL7127284 | 0.74 | MAPT (0.43) | ACHEBCHEPKMMAPTKMT2A | |
| SCHEMBL9269925 | 0.73 | CYP1A2 (0.51) | MAPTKMT2AMEN1RAB9ACYP1A2 | |
| SCHEMBL6926341 | 0.72 | KMT2A (0.48) | ACHEBCHEPKMMAPTKMT2A | |
| SCHEMBL11273163 | 0.72 | LOXL2 (0.46) | MAPTKMT2AMEN1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377542-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | Pharmacor Inc. (CA) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002064551-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | PHARMACOR INC. (CA) | 2002-08-22 | — | — | WO | disclosed |