SCHEMBL6926341

SCHEMBL6926341

Cc1ccc(S(=O)(=O)N[C@@](C)(Cc2ccc([N+](=O)[O-])cc2)C(N)=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
MMP1 P03956 3/20 0.47
MMP2 P08253 3/20 0.47
MMP9 P14780 3/20 0.47
MMP8 P22894 3/20 0.47
MMP13 P45452 3/20 0.47
RAB9A P51151 3/20 0.46
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
PKM P14618 1/20 0.45
GHSR Q92847 1/20 0.45
MAPT P10636 3/20 0.45
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.45
KDM1A O60341 1/20 0.45
MAOA P21397 1/20 0.45
HPGD P15428 1/20 0.44
NPC1 O15118 1/20 0.44
TNF P01375 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6925851 0.91 ALDH1A1 (0.48) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL6912845 0.88 GAA (0.52) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL27713867 0.77 F2 (0.50) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL6802675 0.75 MAPT (0.46) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL6255018 0.74 GHSR (0.46) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL6255022 0.74 GHSR (0.46) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL15199343 0.73 ACHE (0.53) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL14676346 0.73 CA2 (0.56) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL27514491 0.73 MEN1 (0.43) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL9308189 0.72 LOXL2 (0.50) KMT2AMEN1MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed