Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377973 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTKMT2ACYP1A2 | |
| SCHEMBL3393144 | 0.88 | L3MBTL1 (0.47) | ALDH1A1KDM4EMAPTKMT2ACYP1A2 | |
| SCHEMBL8906911 | 0.75 | MT-CO2 (0.50) | ALDH1A1KDM4EMAPTKMT2ACYP1A2 | |
| SCHEMBL30589700 | 0.75 | KDM4E (0.48) | ALDH1A1KDM4EMAPTKMT2ACYP1A2 | |
| SCHEMBL8907774 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2ANPSR1POLB | |
| SCHEMBL8907400 | 0.71 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL8906469 | 0.71 | MAPT (0.47) | ALDH1A1KDM4EMAPTKMT2ACYP1A2 | |
| SCHEMBL6550297 | 0.70 | L3MBTL1 (0.39) | ALDH1A1MAPTKMT2ANPSR1LMNA | |
| SCHEMBL27807438 | 0.69 | POLB (0.45) | ALDH1A1KDM4EMAPTKMT2ACYP1A2 | |
| SCHEMBL8906567 | 0.69 | MAPK1 (0.66) | ALDH1A1KDM4EMAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102048718-A | Medical application of enamine ketone compound | ZEJUN WANG | 2011-05-11 | — | — | CN | disclosed |
| EP-1027055-B1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | UNIV HOWARD (US) | 2004-01-07 | — | — | EP | disclosed |
| EP-1027055-A4 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | UNIV HOWARD (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-1027055-A1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | HOWARD UNIVERSITY (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5994349-A | ANTIEPILEPTIC AGENTS | HOWARD UNIVERSITY (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1999021560-A1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4[10H]-ONE DERIVATIVES | HOWARD UNIVERSITY (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5580894-A | NERVOUS SYSTEM DISORDERS | HOWARD UNIVERSITY (US) | 1996-12-03 | — | — | US | disclosed |