SCHEMBL6545164

SCHEMBL6545164

CCCCCCCC[Si](CCCC)(CCCC)OC(=O)CCC(=O)O[Si](CCCC)(CCCC)CCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.44
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
LMNA P02545 2/20 0.41
GPR84 Q9NQS5 6/20 0.40
PPARG P37231 6/20 0.40
PPARD Q03181 6/20 0.40
PPARA Q07869 6/20 0.40
HDAC11 Q96DB2 5/20 0.40
TSHR P16473 4/20 0.40
ALDH1A1 P00352 2/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
PTPN1 P18031 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6545816 0.94 DGKA (0.47) DGKACA12CA2CA7CA9
SCHEMBL4644579 0.89 NAAA (0.46) DGKACA12CA2CA7CA9
SCHEMBL4644657 0.89 NAAA (0.46) DGKACA12CA2CA7CA9
SCHEMBL4647907 0.87 DGKA (0.44) DGKACA12CA2CA7CA9
SCHEMBL4642000 0.87 DGKA (0.44) DGKACA12CA2CA7CA9
SCHEMBL4642414 0.87 FAAH (0.43) DGKACA12CA2CA7CA9
SCHEMBL4644124 0.87 FAAH (0.43) DGKACA12CA2CA7CA9
SCHEMBL4644015 0.87 DGKA (0.40) DGKACA12CA2CA7CA9
SCHEMBL4646045 0.87 DGKA (0.40) DGKACA12CA2CA7CA9
SCHEMBL4643224 0.86 NAAA (0.43) DGKACA12CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004005302-A1 PROCESS FOR THE PREPARATION OF ACYLOXYSILANES SIGMA COATINGS B.V. (NL) 2004-01-15 WO disclosed
EP-1378514-A1 Process for the preparation of acyloxysilanes SigmaKalon Group B.V. (NL) 2004-01-07 EP disclosed