SCHEMBL6545305

SCHEMBL6545305

CCc1cccc(OCCF)c1S(N)(=O)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.38
HPGD P15428 1/20 0.37
ATM Q13315 1/20 0.37
DRD1 P21728 1/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA9 Q16790 3/20 0.35
KCNH2 Q12809 3/20 0.35
CA7 P43166 2/20 0.34
TSHR P16473 1/20 0.34
CA14 Q9ULX7 1/20 0.34
DRD2 P14416 1/20 0.34
DRD3 P35462 1/20 0.34
LTB4R Q15722 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3290213 0.83 SMN1; SMN2 (0.43) L3MBTL1MAPTNPSR1SMN1; SMN2HPGD
SCHEMBL6546900 0.83 LMNA (0.41) L3MBTL1NPSR1SMN1; SMN2LMNACA12
SCHEMBL15714461 0.81 CYP2C9 (0.38) SMN1; SMN2DRD1KDM4ECA12CA1
SCHEMBL29469905 0.79 CA2 (0.48) MAPTNPSR1SMN1; SMN2LMNAKDM4E
SCHEMBL29469847 0.79 CA2 (0.44) L3MBTL1MAPTNPSR1ATMCA12
SCHEMBL29469798 0.78 MAPT (0.50) L3MBTL1MAPTSMN1; SMN2LMNACA12
SCHEMBL29469889 0.77 CA1 (0.51) MAPTATMLMNAKDM4ECA12
SCHEMBL12969843 0.77 L3MBTL1 (0.67) L3MBTL1MAPTNPSR1SMN1; SMN2HPGD
SCHEMBL29469791 0.77 RIPK1 (0.48) SMN1; SMN2HTR2AHTR2C
SCHEMBL27919459 0.76 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040157744-A1 Substituted fluoroalkoxyphenylsulfonyl-amino(thio)carbonyltriazolino(thi)ones BAYER CROPSCIENCE AG (DE) 2004-08-12 US disclosed
EP-1379512-A1 SUBSTITUTED FLUORALKOXYPHENYLSULFONYLAMINO(THIO)CARBONYLTRIAZOLINO(THI)ONES Bayer CropScience AG (DE) 2004-01-14 EP disclosed
WO-2002081458-A1 SUBSTITUTED FLUORALKOXYPHENYLSULFONYLAMINO(THIO)CARBONYLTRIAZOLINO(THI)ONES BAYER CROPSCIENCE AG (DE) 2002-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040157744-A1 Substituted fluoroalkoxyphenylsulfonyl-amino(thio)carbonyltriazolino(thi)ones ROS1, RIF1, NAT1 L3MBTL1 228/4885MAPT 2384/4885NPSR1 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.