Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | MAPKAPK3 | Q16644 | 3/20 | 0.39 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.39 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 5/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545189 | 0.80 | MAPKAPK2 (0.46) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL6545463 | 0.77 | TTK (0.43) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL6545805 | 0.73 | CDK4 (0.42) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL5374570 | 0.73 | MAP2K4 (0.59) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL2855850 | 0.69 | MAP2K4 (0.59) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL13927625 | 0.66 | IDO1 (0.63) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL2861069 | 0.66 | ALPL (0.54) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL2861016 | 0.66 | ITK (0.68) | MAPKAPK2TTKMAPK8 | |
| SCHEMBL13635799 | 0.65 | MAPKAPK2 (0.45) | MAPKAPK2MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL2871320 | 0.65 | PDPK1 (0.66) | MAPKAPK2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380576-A1 | NOVEL 1H-INDAZOLE COMPOUND | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |