Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 5/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545189 | 0.94 | MAPKAPK2 (0.46) | TTKMAPKAPK2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6545805 | 0.85 | CDK4 (0.42) | TTKMAPKAPK2PRKAB2PRKAG1PRKAA2 | |
| Hydrochloric Acid SCHEMBL8355698 | 0.79 | OPRM1 (0.44) | — | |
| SCHEMBL6545642 | 0.77 | MAPKAPK2 (0.41) | TTKMAPKAPK2MAP2K4CDK4CCNA2 | |
| SCHEMBL5374570 | 0.75 | MAP2K4 (0.59) | TTKMAPKAPK2MAP2K4CDK4CCNA2 | |
| SCHEMBL2855850 | 0.71 | MAP2K4 (0.59) | MAPKAPK2MAP2K4CDK4CCNA2CCND1 | |
| SCHEMBL2867415 | 0.71 | ULK1 (0.64) | MAPKAPK2 | |
| SCHEMBL6545151 | 0.70 | TTK (0.49) | TTKMAPK8 | |
| SCHEMBL5388479 | 0.69 | TTK (0.45) | TTKMAPKAPK2MAP2K4MAPK1MAPKAPK3 | |
| SCHEMBL13927625 | 0.68 | IDO1 (0.63) | TTKMAPKAPK2MAP2K4CDK4CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380576-A1 | NOVEL 1H-INDAZOLE COMPOUND | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |