Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282523 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL2045622 | 0.93 | ALDH1A1 (0.42) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL5881508 | 0.87 | ALDH1A1 (0.40) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL27600073 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL5548791 | 0.77 | RARG (0.30) | POLBGAAGFER | |
| SCHEMBL5413341 | 0.76 | GLRA1 (0.44) | ALDH1A1MAPTADRA1AMAPK1 | |
| SCHEMBL7592828 | 0.72 | ALDH1A1 (0.41) | ALDH1A1GAACA1CA2CA7 | |
| SCHEMBL8119851 | 0.72 | NFE2L2 (0.43) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL13395132 | 0.71 | CYP2D6 (0.42) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL739698 | 0.70 | HDAC4 (0.48) | ALDH1A1TSHRPOLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373239-A1 | BENZOFURAN DERIVATIVES | Bayer HealthCare AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079181-A1 | BENZOFURAN DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |