Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282523 | 0.72 | ALDH1A1 (0.38) | ALDH1A1GAACA1CA2LPAR1 | |
| SCHEMBL278306 | 0.72 | NR3C2 (0.49) | ALDH1A1GAACYP3A4LMNATP53 | |
| SCHEMBL10352726 | 0.71 | RARA (0.61) | ALDH1A1GAACYP3A4LMNATP53 | |
| SCHEMBL1038127 | 0.70 | ACHE (0.58) | ALDH1A1GAACYP3A4LMNATP53 | |
| SCHEMBL1535615 | 0.70 | HPGD (0.48) | ALDH1A1GAACYP3A4LMNATP53 | |
| SCHEMBL799846 | 0.70 | ALDH1A1 (0.70) | ALDH1A1GAACYP3A4LMNATP53 | |
| SCHEMBL9885329 | 0.69 | L3MBTL1 (0.46) | ALDH1A1GAACYP3A4LMNATP53 | |
| SCHEMBL7545720 | 0.69 | HTR2A (0.42) | HTR2A | |
| SCHEMBL61547 | 0.68 | ALDH1A1 (0.73) | ALDH1A1GAACYP3A4LMNATP53 | |
| SCHEMBL1542948 | 0.68 | PTGDR2 (0.56) | ALDH1A1GAACYP3A4LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002044120-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR III | KARO BIO AB (SE) | 2002-06-06 | — | — | WO | disclosed |