Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045622 | 0.90 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTPOLBGAA | |
| SCHEMBL282523 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTPOLBGAA | |
| SCHEMBL6545793 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTPOLBGAA | |
| SCHEMBL8119851 | 0.70 | NFE2L2 (0.43) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL13395132 | 0.68 | CYP2D6 (0.42) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL6545093 | 0.67 | CA1 (0.48) | ALDH1A1MAPTGAATHRBCA1 | |
| SCHEMBL739698 | 0.67 | HDAC4 (0.48) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL487152 | 0.67 | CYP2D6 (0.67) | ALDH1A1MAPTGAATHRBRORC | |
| SCHEMBL29591727 | 0.67 | ACHE (0.58) | ALDH1A1TSHRPOLBGAAGFER | |
| SCHEMBL10238859 | 0.67 | ACHE (0.58) | ALDH1A1TSHRPOLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015246-B2 | Benzofuran derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2006-03-21 | — | — | US | disclosed |
| US-20040220415-A1 | Benzofuran derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1373239-A1 | BENZOFURAN DERIVATIVES | Bayer HealthCare AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079181-A1 | BENZOFURAN DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220415-A1 | Benzofuran derivatives | BPTF, ABCG2, ABCB1 | ALDH1A1 485/4885TSHR 4652/4885MAPT 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.