Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545424 | 0.95 | EPHX2 (0.43) | EPHX2CES2CES1KDM4EMEN1 | |
| SCHEMBL9295317 | 0.91 | KDM4E (0.47) | EPHX2CES2CES1KDM4EMEN1 | |
| SCHEMBL6555700 | 0.86 | KDM4E (0.40) | EPHX2CES2CES1KDM4EMEN1 | |
| SCHEMBL6545706 | 0.85 | NAAA (0.43) | EPHX2CES2CES1NAAAEPHX1 | |
| SCHEMBL6555337 | 0.84 | KDM4E (0.38) | EPHX2CES2CES1KDM4EMEN1 | |
| SCHEMBL6555670 | 0.82 | KDM4E (0.37) | EPHX2CES2CES1KDM4EMEN1 | |
| SCHEMBL5839081 | 0.81 | TSHR (0.44) | EPHX2CES2CES1NAAAEPHX1 | |
| SCHEMBL1746085 | 0.80 | CES2 (0.49) | EPHX2CES2CES1KDM4EMEN1 | |
| SCHEMBL1746452 | 0.80 | CES2 (0.49) | EPHX2CES2CES1KDM4EMEN1 | |
| SCHEMBL14312713 | 0.80 | CES2 (0.49) | EPHX2CES2CES1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |