SCHEMBL6555337

SCHEMBL6555337

[CH2]CCC(=O)O[Si](CCCC)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
EPHX2 P34913 1/20 0.35
HPGD P15428 1/20 0.35
PTGS2 P35354 1/20 0.34
NAAA Q02083 1/20 0.34
TSHR P16473 2/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MIF P14174 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9295317 0.90 KDM4E (0.47) KDM4EMEN1RECQLKMT2ACES2
SCHEMBL6545424 0.85 EPHX2 (0.43) KDM4EMEN1RECQLKMT2ACES2
SCHEMBL6555700 0.84 KDM4E (0.40) KDM4EMEN1RECQLKMT2ACES2
SCHEMBL6546221 0.84 EPHX2 (0.42) KDM4EMEN1RECQLKMT2ACES2
SCHEMBL6555670 0.84 KDM4E (0.37) KDM4EMEN1RECQLKMT2ACES2
SCHEMBL6554056 0.82 NAAA (0.37) KDM4EMEN1RECQLKMT2ACES2
SCHEMBL6554058 0.80 PTGS2 (0.39) CES2CES1EPHX2PTGS2NAAA
SCHEMBL6874699 0.79 TSHR (0.39) CES2CES1EPHX2NAAATSHR
SCHEMBL28852412 0.78 THRB (0.44) CES2CES1EPHX2HPGDNAAA
SCHEMBL6555334 0.75 ZDHHC2 (0.37) KDM4EMEN1RECQLKMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed