Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554058 | 0.94 | PTGS2 (0.39) | NAAAEPHX1ALDH1A1EPHX2HTT | |
| SCHEMBL704041 | 0.92 | L3MBTL1 (0.41) | ALDH1A1TSHRCES2CES1PTGS2 | |
| SCHEMBL708241 | 0.89 | L3MBTL1 (0.41) | ALDH1A1TSHRCES2CES1PTGS2 | |
| SCHEMBL707770 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNACES2CES1PTGS2 | |
| SCHEMBL5839081 | 0.87 | TSHR (0.44) | NAAAEPHX1ALDH1A1EPHX2HTT | |
| SCHEMBL6545424 | 0.86 | EPHX2 (0.43) | NAAAEPHX1ALDH1A1EPHX2HTT | |
| SCHEMBL6546221 | 0.85 | EPHX2 (0.42) | NAAAEPHX1ALDH1A1EPHX2HTT | |
| SCHEMBL702608 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TSHRCES2CES1PTGS2 | |
| SCHEMBL11339624 | 0.84 | NAAA (0.43) | NAAAEPHX1ALDH1A1EPHX2HTT | |
| SCHEMBL5838825 | 0.82 | THRB (0.48) | NAAAEPHX1ALDH1A1EPHX2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |