SCHEMBL6548084

SCHEMBL6548084

Cc1ccc(C(C)C(C)Cc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.52
TRPA1 O75762 2/20 0.50
SIGMAR1 Q99720 5/20 0.45
TAAR1 Q96RJ0 4/20 0.45
SLC6A2 P23975 3/20 0.45
SLC6A4 P31645 2/20 0.45
SLC6A3 Q01959 2/20 0.45
MAOA P21397 1/20 0.45
CYP2A6 P11509 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
CNR2 P34972 2/20 0.42
CNR1 P21554 1/20 0.42
SLC18A2 Q05940 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HTT P42858 1/20 0.40
CYP2C19 P33261 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547617 0.92 SMN1; SMN2 (0.50) CYP2D6TRPA1SIGMAR1TAAR1SLC6A2
SCHEMBL6546282 0.88 CYP2D6 (0.59) CYP2D6TRPA1SIGMAR1TAAR1SLC6A2
SCHEMBL17118252 0.81 SIGMAR1 (0.42) CYP2D6TRPA1SIGMAR1TAAR1SLC6A2
SCHEMBL11034962 0.81 TRPA1 (0.53) CYP2D6TRPA1SIGMAR1TAAR1SLC6A2
SCHEMBL5313594 0.80 ESR1 (0.53) CYP2D6TRPA1SIGMAR1TAAR1SLC6A2
SCHEMBL29938176 0.79 SLC6A2 (0.55) CYP2D6SIGMAR1TAAR1SLC6A2SLC6A4
Ammonia Solution, Strong SCHEMBL5308343 0.78 ESR1 (0.52) CYP2D6TRPA1SIGMAR1TAAR1SLC6A2
SCHEMBL2843913 0.78 ALDH1A1 (0.49) CYP2D6SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL2053141 0.78 SLC6A2 (0.59) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL12867099 0.78 CYP2C19 (0.46) CYP2D6TRPA1SIGMAR1TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed