SCHEMBL6546499

SCHEMBL6546499

CCc1ccccc1C=Cc1ccc(C)cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
HSP90AA1 P07900 1/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NFE2L2 Q16236 2/20 0.36
CHAT P28329 1/20 0.36
NQO2 P16083 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9166262 0.85 CHAT (0.42) KDM4ELMNARAB9ACYP1A1CYP1B1
SCHEMBL9166255 0.85 CHAT (0.42) KDM4ELMNARAB9ACYP1A1CYP1B1
SCHEMBL2484811 0.83 ALDH1A1 (0.50) MAPTKDM4EKMT2ASMN1; SMN2LMNA
SCHEMBL2484812 0.83 ALDH1A1 (0.50) MAPTKDM4EKMT2ASMN1; SMN2LMNA
SCHEMBL19231487 0.83 ALDH1A1 (0.50) MAPTKDM4EKMT2ASMN1; SMN2LMNA
SCHEMBL10790780 0.83 KDM4E (0.36) MAPTKDM4EKMT2ASMN1; SMN2LMNA
SCHEMBL6546342 0.81 RAB9A (0.47) MAPTKDM4EKMT2ASMN1; SMN2LMNA
SCHEMBL3314625 0.81 CHAT (0.47) MAPTKMT2ALMNAMEN1TDP1
SCHEMBL6546259 0.81 CHAT (0.47) MAPTKMT2ALMNAMEN1TDP1
SCHEMBL11323718 0.79 AMY1A (0.47) MAPTKDM4EKMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed