SCHEMBL6546342

SCHEMBL6546342

Cc1ccc(C=Cc2ccccc2C)c(C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.47
KDM4E B2RXH2 4/20 0.47
APOBEC3A P31941 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
POLB P06746 3/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ALOX12 P18054 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PABPC1 P11940 1/20 0.46
NQO2 P16083 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546420 0.89 AMY1A (0.47) RAB9AKDM4EALDH1A1MEN1KMT2A
SCHEMBL11323718 0.89 AMY1A (0.47) RAB9AKDM4EALDH1A1MEN1KMT2A
SCHEMBL28631650 0.84 TRPA1 (0.50) RAB9AKDM4EALDH1A1TSHRMEN1
SCHEMBL29189279 0.83 ALDH1A1 (0.43) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL6547378 0.83 NFE2L2 (0.51) RAB9AKDM4EAPOBEC3AAPOBEC3GALDH1A1
SCHEMBL1589395 0.83 ALDH1A1 (0.62) RAB9AKDM4EAPOBEC3AAPOBEC3GALDH1A1
SCHEMBL16105579 0.83 NFE2L2 (0.51) RAB9AKDM4EAPOBEC3AAPOBEC3GALDH1A1
SCHEMBL1035353 0.83 ALDH1A1 (0.62) RAB9AKDM4EAPOBEC3AAPOBEC3GALDH1A1
SCHEMBL16105505 0.83 NFE2L2 (0.51) RAB9AKDM4EAPOBEC3AAPOBEC3GALDH1A1
SCHEMBL6546499 0.81 MAPT (0.43) RAB9AKDM4EMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed