Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095518 | 0.86 | TLR8 (0.44) | TLR8HTR2ALMNAHTTLIPG | |
| SCHEMBL6547306 | 0.85 | HTR2A (0.59) | TLR8HTR2ALMNAHTTLIPG | |
| SCHEMBL7861886 | 0.84 | CALM1 (0.52) | HTR2ACNR2GPR55HRH1CALM1 | |
| SCHEMBL10982682 | 0.84 | LIPG (0.45) | TLR8LIPG | |
| SCHEMBL8087736 | 0.81 | TLR8 (0.43) | TLR8HTR2ALMNAHTTLIPG | |
| SCHEMBL8093734 | 0.81 | HTR2A (0.55) | TLR8HTR2ALMNAHTTLIPG | |
| SCHEMBL6546124 | 0.81 | TP53 (0.46) | HTR2ACNR2GPR55CALM1 | |
| SCHEMBL8095162 | 0.81 | TLR8 (0.49) | TLR8HTR2ACNR1CNR2LIPG | |
| SCHEMBL7114512 | 0.79 | ALOX5 (0.46) | HTR2ACNR2GPR55CALM1 | |
| SCHEMBL22471642 | 0.79 | HTR2A (0.57) | TLR8HTR2ALMNAHTTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |